The active ingredients in Ginkgo biloba extracts are flavonoid glycosides and terpene lactone, which are present in concentrations of ≥24% and ≥6%, respectively. Current common analytical methods involve a hydrolysis step that converts flavonoid glycosides into aglycones. However, many aglycones are absent in the original ginkgo plant, yet they are used as quality control indicators for Ginkgo biloba products.
Now let’s see how they present in the HPLC figure.