How to Ensure You’re Buying Genuine Ginkgo Biloba Extracts

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Ginkgo Biloba Extract And Its Health Benefits

Ginkgo Biloba Extract is derived from the leaves of the ginkgo and contains active ingredients such as Ginkgo flavone glycosides and terpenoids. These ingredients are believed to have various health benefits, including vasodilation, regulation of blood lipids, inhibition of platelet activating factor, prevention of thrombosis, and scavenging of free radicals. Numerous clinical studies have demonstrated that standardized Ginkgo Biloba Extract can significantly reduce the symptoms of mental disorders such as Alzheimer’s disease. 
 

Reasons For The Emergence Of Counterfeit Products

Natural products are often considered to be a natural way to correct and improve people’s health systems. Unfortunately, the competitive environment has led to the emergence of counterfeit products in the market.

The active ingredients in Ginkgo Biloba Extract are flavonoid glycosides and terpene lactone, which are present in concentrations of ≥24% and ≥6%, respectively. Current common analytical methods involve a hydrolysis step that converts flavonoid glycosides into aglycones. However, many aglycones are absent in the original ginkgo plant, yet they are used as quality control indicators for Ginkgo biloba products. These inappropriate quality control indicators provide opportunities for adulterating Ginkgo Biloba Extract

Common Adulteration Methods

Adulteration of Ginkgo Biloba Extracts can occur in various ways, with the most common being the addition of specific plant extracts or the inclusion of certain percentages of flavonoid glycosides and aglycones to meet the requirement of 24% flavonoids. Rutin, quercetin, kaempferol, and isorhamnetin are the most commonly used ingredients. Another type of adulteration involves the use of other parts of the Ginkgo tree, such as roots, bark, or seeds.

Among the aforementioned adulteration methods, the use of other plant extracts rich in flavonoids is the most common. Sophora japonica pods and sophorae flos are rich in rutin and quercetin, but also contain genistein and genistin, which are absent in Ginkgo Biloba Extracts. If Sophora japonica pods or sophorae flos are used to adulterate Ginkgo Biloba Extracts, these compounds will be detected in the analysis.

How to Avoid Inferior Products

To determine whether a Ginkgo Biloba Extract is adulterated, the following methods can be used: 
 

1.Test The Sample Using Non-Hydrolysis Detection Method

If the sample contains 13 aglycone peaks, and the peak heights and distribution between each peak are similar to those of the raw materials, and there are no peaks corresponding to genistein, genistin, quercetin, kaempferol and isorhamnetin, the sample can be judged as not adulterated. (see below)
 
P7:Ginkgo Biloba Raw Materials
P28: Ginkgo Biloba Standard Extract
 

2.Thin—Layer Chromatography

1: Ginkgo Biloba Extract (Adulterated Product)
2: Ginkgo Biloba Leaf Raw Material 
3: Ginkgo Biloba Standard Extract
4-7: Ginkgo Biloba Extract (Adulterated Product)
8: Sophora Japonica Pods Extract
9: Sophora Japonica Pods(Hydrolysis With Acid)

From the thin layer chromatography, it can be observed that the adulterated Ginkgo Biloba Extract will show obvious characteristic spots of hydrolyzed sophora japonica pods or sophora japonica pods.

CANGJIA prides ourselves on providing the most authentic Ginkgo Biloba Extract. If you’re looking to source high-quality Ginkgo Biloba Extract, contact us today to discuss your requirements and get a free quote. Our team of experts will work closely with you to ensure that you get exactly what you need.

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